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Wigan Athletic will turn to goalkeeper Matt Gilks, after Stoke City loanee Jakob Haugaard tore a shoulder muscle and returned to his parent club.
Striker Omar Bogle and defender Reece Burke could figure despite their recent injury issues.
Cardiff City manager Neil Warnock says a sickness bug has affected his squad’s preparations for the game and will rule out defender Declan John.
Striker Rickie Lambert could be back after a back injury.
The Latics will be relegated if they lose to Cardiff and Nottingham Forest beat Huddersfield. Graham Barrow’s side could also be relegated if they draw, if Forest are win and Blackburn draw or win against Wolves.
Striker Nick Powell could continue in his “super-sub” role with five goals in his last three games, despite Wigan’s perilous circumstances and his recent return from a hamstring injury.
Paul Rowley, BBC Radio Manchester
Frankly, Graham Barrow’s side need to win their final three games if they’ve got any chance of surviving the drop after a miserable return to the Championship since lifting the League One title last season.
The ‘Tics, still five points from safety, have shown plenty of spirit in the run-in, winning two of their last three matches.
The worry for the interim Wigan manager is that they’ve conceded at least two goals in each of his six games in charge, and he knows that Cardiff boss Neil Warnock won’t allow his side to roll over, even though they’re safe in mid-table.
- Wigan have won four of their last six home league games against Cardiff (W4 D1 L1).
- Cardiff have won two of their last three league clashes with Wigan (L1), as many as they’d enjoyed in their previous 19 combined.
- Nick Powell has scored in each of his last three appearances for Wigan, netting five goals – all as a substitute. Prior to this run, Powell had scored two goals in 43 previous sub appearances in the league football, including one against Wigan for Manchester United in September 2012.
- Neil Warnock has ended up on the losing side in five of his last six Football League encounters with Wigan, with the other a 1-0 win in the Premier League as Sheffield United manager in December 2006.
- Michael Jacobs has scored in three Championship games this season and has ended up on the losing side in every game.
- The Bluebirds are winless in five away league games (D2 L3) since winning back to back games against Leeds and Derby.