Defender Tim Fosu-Mensah suffered a shoulder problem in that game and joins a lengthy injury list, which includes midfielders Paul Pogba and Juan Mata.
Swansea midfielder Jack Cork and defender Martin Olsson are expected to return after recovering from respective ankle and hamstring injuries.
Wayne Routledge is ruled out after having a hernia operation on Tuesday.
MOTD COMMENTATOR’S NOTES
Simon Brotherton: “Manchester United’s push for a top-four finish continues against a Swansea side who are currently two points from safety in their battle to avoid the drop.
“United equalled their longest ever unbeaten run in the top flight with Thursday’s draw in the Manchester derby, making it 24 matches without defeat in the league.
“Holding them back has been the frustrating number of draws, which includes five of the last seven Premier League games at Old Trafford.
“Swansea’s win over Stoke last week was their first in seven, giving them renewed hope of survival and they have enjoyed some success against this weekend’s opponents in the recent past, winning on two of their last four visits.”
WHAT THE MANAGERS SAY
Swansea head coach Paul Clement: “United have been playing Thursday and Sunday for many weeks now and they have an injury list which I’m sure the manager is not happy with.
“But we know it will not be easy. You always hope when you play a big team at their stadium that they have a slightly off-day and you have a chance.”
Swansea need a win but, although they have beaten Manchester United home or away in each of the past three seasons, I don’t see them doing it again on Sunday.
- Think you can do better than Lawro? Predict the score for this match and the rest of this round’s Premier League fixtures in our Predictor game
- Manchester United have won their last two league meetings with Swansea, who had won the previous three in a row.
- After failing to win any of their first 10 visits to Old Trafford in all competitions (D2, L8), the Swans have won on two of their last four.
- United can set a new club record of 25 matches unbeaten in a single top-flight season.
- They have kept eight clean sheets in their last 11 league games.
- The Red Devils have drawn five of their eight matches at Old Trafford against sides currently in the bottom half of the table – compared to nine wins from 10 meetings away from home.
- No ground has staged more draws in the Premier League this season than the nine at Old Trafford. United have only once drawn more often at home in a campaign: 11 times in 1980-81.
- Swansea’s win over Stoke ended a run of six games without a victory (D1, L5).
- The Swans have picked up just seven points from their last 48 available on the road in the Premier League and have failed to score in each of their last three away games.
- Paul Clement has won six of his 15 Premier League games in charge of the Swans, giving him the best win ratio of any manager for the Welsh side in the competition (40%).
- Gylfi Sigurdsson could become the first player to score in three consecutive Premier League away appearances at Old Trafford since Sergio Aguero in April 2015.
|Most probable score: 2-0||Probability of draw: 18%|
|Probability of home win: 73%||Probability of away win: 9%|
SAM (Sports Analytics Machine) is a super-computer created by @ProfIanMcHale at the University of Salford that is used to predict the outcome of football matches.